| Teams 2022 AdventHealth 400 |
|---|
| No. | Team | Driver | Mfg |
|---|---|---|---|
| 1 | Trackhouse Racing | Ross Chastain | Chevrolet |
| 2 | Team Penske | Austin Cindric | Ford |
| 3 | Richard Childress Racing | Austin Dillon | Chevrolet |
| 4 | Stewart Haas Racing | Kevin Harvick | Ford |
| 5 | Hendrick Motorsports | Kyle Larson | Chevrolet |
| 6 | Roush Fenway Racing | Brad Keselowski | Ford |
| 7 | Spire Motorsports | Corey LaJoie | Chevrolet |
| 8 | Richard Childress Racing | Tyler Reddick | Chevrolet |
| 9 | Hendrick Motorsports | Chase Elliott | Chevrolet |
| 10 | Stewart Haas Racing | Aric Almirola | Ford |
| 11 | Joe Gibbs Racing | Denny Hamlin | Toyota |
| 12 | Team Penske | Ryan Blaney | Ford |
| 14 | Stewart Haas Racing | Chase Briscoe | Ford |
| 15 | Rick Ware Racing | JJ Yeley | Ford |
| 16 | Kaulig Racing | Noah Gragson | Chevrolet |
| 17 | Roush Fenway Racing | Chris Buescher | Ford |
| 18 | Joe Gibbs Racing | Kyle Busch | Toyota |
| 19 | Joe Gibbs Racing | Martin Truex, Jr. | Toyota |
| 20 | Joe Gibbs Racing | Christopher Bell | Toyota |
| 21 | Wood Brothers Racing | Harrison Burton | Ford |
| 22 | Team Penske | Joey Logano | Ford |
| 23 | 23XI Racing | Bubba Wallace | Toyota |
| 24 | Hendrick Motorsports | William Byron | Chevrolet |
| 31 | Kaulig Racing | Justin Haley | Chevrolet |
| 34 | Front Row Motorsports | Michael McDowell | Ford |
| 38 | Front Row Motorsports | Todd Gilliland | Ford |
| 41 | Stewart Haas Racing | Cole Custer | Ford |
| 42 | Petty GMS Motorsports | Ty Dillon | Chevrolet |
| 43 | Petty GMS Motorsports | Erik Jones | Chevrolet |
| 45 | 23XI Racing | Kurt Busch | Toyota |
| 47 | JTG Daughtery Racing | Ricky Stenhouse, Jr. | Chevrolet |
| 48 | Hendrick Motorsports | Alex Bowman | Chevrolet |
| 51 | Rick Ware Racing | Cody Ware | Ford |
| 77 | Spire Motorsports | Josh Bilicki | Chevrolet |
| 78 | Live Fast Motorsports | B.J. McLeod | Ford |
| 99 | Trackhouse Racing | Daniel Suarez | Chevrolet |